This research line focuses on the application of control engineering methods to the field of environmental systems, with an emphasis on wastewater treatment processes. The general objective of this research line is to propose new strategies of control and operation in urban Waste Water Treatment Plants (WWTP) with simultaneous elimination of organic matter (DQO), nitrogen (N) and phosphorus (P). The design is based on modelling tools that try to optimize the proposed control strategies through a benchmarking scenario, which should incorporate criteria of quality of the effluent, minimization of economic costs or environmental impact. The consideration of the different criteria is faced through the application of strategies of multi-objective optimization. A Life Cycle Analysis (LCA) methodology is used for the evaluation of the environmental impact.